hrp0094p1-100 | Thyroid A | ESPE2021

Serum fibroblast growth factor 21 (FGF-21) levels of children and adolescents with Hashimoto’s thyroiditis, before and after L-thyroxin medication

Drongitis Pavlos , Kotanidou Eleni P , Serbis Anastasios , Tsinopoulou Vasiliki Rengina , Gerou Spyridon , Galli-Tsinopoulou Assimina ,

Background: Fibroblast growth factor 21 (FGF-21) is a complex molecule involved in lipid and glucose metabolism. FGF-21 shares biochemical pathways and sites of action with thyroid hormones. Current data correlate FGF-21 levels to thyroid function. The aim of the present study was to investigate possible associations among FGF-21 levels, resting metabolic rate (RMR), lipidemic profile and L-thyroxin replacement therapy treatment in children and adolescents wit...